BIOE 1010 introduces students to biomedical engineering, and provides an introduction to possible careers and research topics in biomedical engineering. Students also learn human anatomy by understanding how to incorporate visual human data sets into computer prototyping and design tools.

Grading Basis: Letter Grade

Typically Offered: Fall.

A modern engineer is required to solve problems involving the physical world not only on paper, but also using numerical tools implemented on digital computers. This class introduces the students a first set of numerical algorithms for the solution of calculus-based engineering problems.

Grading Basis: Letter Grade

Requires prerequisite courses of ENGR 1100 and MATH 2411 (all minimum grade C-). Requires corequisite course of MATH 3195 or MATH 3191 or MATH 3200 or permission of instructor.

Covers topics which students may wish to pursue on their own initiative with guidance from department faculty. Credit is awarded upon completion of a project. Department consent required. Repeatable.

Grading Basis: Letter Grade

Repeatable. Max Credits: 6.

Department Consent Required. Restriction: Restricted to BIOE-BS majors.

This course is intended for junior biomedical engineering students to facilitate their development into biomedical engineering investigation. The course has been designed to introduce fundamental principles of circuit theory, analog and digital electronics and biological instrumentation techniques commonly used in biomedical research.

Grading Basis: Letter Grade

Requires prerequisite course of MATH 3195 (minimum grade C-).

This course will offer an overview of solid and fluid mechanics, as applied to biomechanical systems. After completing this course, students should have enough understanding of biomechanics to: (1) perform and interpret basic analytical of biomech. systems: (2) analytically reason through a design: (3) and choose a specialty.

Grading Basis: Letter Grade

Requires prerequisite courses of ENGR and BIOE 2020 (all minimum grade C-).

This course will cover different kinds of biomaterials in biomedical applications, and their physiological response in the biological environment. In addition, it will cover material properties, host response, and characterization techniques.

Grading Basis: Letter Grade

Requires prerequisite courses of ENGR and BIOE 2020 (all minimum grade C-).

This course will introduce students to central concepts in human physiology. This includes the structure, function and homeostatic role of key organs within the body; the engineering principles governing these systems and processes; and designing engineering-based solutions to overcome dysfunction in disease.

Grading Basis: Letter Grade

Requires prerequisite courses of ENGR 1100 and (BIOL 2010 or BIOL 2011) and (BIOL 2020 or BIOL 2021) and (CHEM 3411 or CHEM 3418) (all minimum grade C-).

Typically Offered: Fall.

This course focuses on the quantitative description of biomolecular and cellular dynamics. The building and application of mechanistic models of biological processes will be covered including receptor-ligand binding, enzymatic reactions, signal transduction pathways, gene expression, cell growth and death, and pharmacokinetics. Mathematical and computational approaches of dynamical systems are used to analyze and design complex biological networks.

Grading Basis: Letter Grade

Requires prerequisite courses of ENGR 1100, BIOE 2020, CHEM 2031, CHEM 2038, CHEM 2061, CHEM 2068, MATH 3195, BIOL 2020, and BIOL 2021 (all minimum grade C-).

Students will learn and apply parametric statistics, including t-tests, ANOVA, and regression methods, using commercially available statistical software to the analysis of clinical and/or biological data. Further, they will be introduced to measurement error and the propagation of error technique.

Grading Basis: Letter Grade

Typically Offered: Spring.

Core biomedical engineering lab required of all major students. This lab introduces students to experimental techniques in the areas of Biomaterials, Biomedical Instrumentation, and Biomechanics.

Grading Basis: Letter Grade

Requires prerequisite courses of CHEM 3411 or CHEM 3418 (all minimum grade C-).

Lab sequence 2 of 2. A series of modules focused on quantitative techniques relative to Biomedical Engineering. Modules will include Physiological data acquisition and analysis, Medical Imaging and Assistive Technologies.

Grading Basis: Letter Grade

Requires prerequisite courses of BIOE 2020 and BIOE 3010 and MATH 2411 (all minimum grade C-).

BioDesign I is the first course in a three sequence design process that provides students with a framework for identifying medical needs through clinical observation, environment analysis and product screening.

Grading Basis: Letter Grade

Prereq: BIOE 3010, 3020, 3030, 3040 with a C- or higher.

Department of Bioengineering Internship. Credit may be applied toward technical electives in the BS in Bioengineering degree. Department consent required. Repeatable. Semester Hours: 1 to 3

Grading Basis: Letter Grade

Repeatable. Max Credits: 6.

Department Consent Required. Restriction: Restricted to BIOE-BS majors.

This represents the second semester of the core undergraduate Biodesign sequence. Students gain experience around Design and Prototyping, Verification and Validation, and evaluation of key components around biomedical technology development.

Grading Basis: Letter Grade

Prereq: BIOE 3090 with a C- or higher.

The course focuses on the design and construction of microprocessor-controlled electro-mechanical systems. Lectures review critical circuit topics (Ohm’s law, RLC circuits, DC and AC signals, diode and transistor circuits, operational amplifiers, and digital signals), introduce microprocessor architecture and programming, discuss sensor and actuator component selection, robotic systems, and design strategies for complex, multi-system devices. Lab work reinforces lectures and allows hands-on experience with robotic and embedded systems design. Students must design and build an embedded systems device related to assistive technology. Cross-listed with BIOE 5039.

Grading Basis: Letter Grade

This course represents the capstone culmination of the core undergraduate Biodesign experience. Students finalize all design, prototyping, testing and validation components, and present the project per professional standards to professionals and peers.

Grading Basis: Letter Grade

Prereq: BIOE 4035 with a C- or higher.

Undergraduate overview of optical imaging, ranging from classical microscopy to advanced, non-linear techniques and includes theory, technology and applications in biomedical sciences. This will prepare students for developing and applying state-of-the-art optical imaging in their research. Cross-listed with BIOE 5053.

Grading Basis: Letter Grade

Requires prerequisite courses of PSYS 2311 and PHYS 2331 and MATH 2421 (minimum grade D-).

This course is designed to introduce the regulations that govern the design, testing, approval, and sale of medical products. Cross-listed with BIOE 5054.

Grading Basis: Letter Grade

This course introduces the quality assurance standards and design controls that guide the medical products industry. Cross-listed with BIOE 5055.

Grading Basis: Letter Grade

Typically Offered: Fall.

This course provides students with an overview of technologies and their use by and for persons with disabilities. Cross-listed with BIOE 5057.

Grading Basis: Letter Grade

This course provides an introduction to the topic of disability and aging and the application of bioengineering principles for persons living with functional impairment(s) across the lifespan. Cross-listed with BIOE 5058.

Grading Basis: Letter Grade

This course instills in the 3D modeling skills specific to the biomedical industry. Topics include computer aided design (CAD), medical imaging, image processing, patient specific image to three-dimensional (3D) model reconstruction, non-uniform rational b-spline (NURBS) surfaces, finite element and computational fluid dynamics (FEA/CFD) analyses and physical modeling using rapid prototyping.

Grading Basis: Letter Grade

Prereq: BIOE 3010, 3020, 3030, 3040 with a C- or higher.

Typically Offered: Fall, Spring.

This course focus on the practical application of MATLAB in bioengineering and life sciences contexts, although the material is more broadly applicable. Specific topics include error handling and debugging; graphical user interfaces and advanced plotting; image processing; statistics; modeling and model fitting; time-series signal analysis; data management; as well as code profiling, performance optimization, and parallel computing. Cross-listed with BIOE 5064

Grading Basis: Letter Grade

Requires prerequisite courses of MATH 2411 and BIOE 2020 and BIOE 3071 (minimum grade C-).

This course provides an introduction to human factors testing and evaluation in the context of medical devices and assistive technology (AT). Particular focus will be given towards designing and applying usability testing to inform product design decisions or improvements. Topics include human factor considerations for aging and disabled populations (and their care providers), usability techniques, user experience data collection and interpretation, etc. Students will engage in hands-on human factors assessments such as contextual inquiry of surgery patients, cognitive walkthroughs with simulating disability, and product usability testing and iteration.

Grading Basis: Letter Grade

This course will introduce undergraduates to the basic physics, technologies, and clinical methodologies underlying Ultrasound, MRI, CT, PET and SPECT imaging systems. The course will include lectures, and visits to campus hospital and research imaging systems as well as hands on ultrasound labs. Cross-listed with BIOE 5068.

Grading Basis: Letter Grade

This course covers fundamental fluid mechanics concepts with a focus on biological and biomedical applications. Students will learn to solve fluid mechanics problems with both analytical approaches and computational fluid dynamics simulations in Solidworks. 3 Credits. Cross-listed with BIOE 5069

Grading Basis: Letter Grade

Requires prerequisite courses of BIOE 2020 and BIOE 3071 (all minimum grade D-).

This course will introduce undergraduates to topics in neural interfaces (Brain machine interfaces, peripheral nerve interfaces etc), the issues involved in the design of mechatronic limb systems and the decoding algorithms used to map the neural interface to the mechatronic limb. Cross-listed with BIOE 5073.

Grading Basis: Letter Grade

Requires prerequisite course of BIOE 3010 (minimum grade C-).

This course will introduce undergraduate students to fundamental synthetic method and basic characteristics of various polymeric biomaterials and their crucial roles in different biomedical applications. It will also cover how the polymers can be modified to enhance biomedical applications. Cross-listed with BIOE 5083.

Grading Basis: Letter Grade

This course covers tools, techniques, characterization and applications in modern tissue engineering. Cross-listed with BIOE 5085.

Grading Basis: Letter Grade

This course is designed to provide learners with an overview of quality assurance and regulatory affairs functions after a product has been cleared or approved for sale. Cross-listed with BIOE 5075

Grading Basis: Letter Grade

Requires prerequisite courses of (BIOE 5054 or BIOE 4054) and (BIOE 5055 or BIOE 4055) (all minimum grade D-).

Typically Offered: Fall, Spring.

This capstone course will connect concepts across the product lifecycle using examples in medical devices, pharmaceuticals, and biologics. It will include a 3-day, in-person experiential learning activity hosted by our industry partners and enrollment in an established mentorship program through the Colorado Bioscience Institute. Cross-listed with BIOE 5095

Grading Basis: Letter Grade

Requires prerequisite courses of (BIOE 5054 or BIOE 4054) and (BIOE 5055 or BIOE 4055) (all minimum grade D-).

This course provides an overview of basic and advanced image processing algorithms from both a theoretical and a practical perspective with special emphasis in Bioengineering. Topics to be covered include quantization, filtering, texture analysis, Fourier transform, wavelets, morphological operations, image registration, segmentation, machine learning, deep learning, and principal component analysis (PCA). Cross-listed with BIOE 5100.

Grading Basis: Letter Grade

Typically Offered: Spring.

This course will introduce the important processes needed to implement a medical device into a viable entrepreneurial venture with strong focus on the themes of disruption and innovation, investment readiness of a product idea (traction), business and risk analysis, and funding your ideas. At the same time, we will explore your entrepreneurial personality through the three lenses of personal motivation, work passion, and superpowers. Cross-listed with BIOE 5300.

Grading Basis: Letter Grade

Typically Offered: Fall.

Laboratory experience in genetic engineering including molecular cloning, gene delivery, and genome editing. Students will work on open ended projects that may include the expression of recombinant proteins, silencing RNA, or the knockdown or insertion genes into the genome. Cross-listed with BIOE 5400.

Grading Basis: Letter Grade

Requires prerequisite courses of CHEM 2031 and 2038 and 2061 and 2068 and 3411 and 3418 and BIOL 2020 and 2021 (all minimum grade D-).

Provides weekly speakers, workshops and other experiences that educate and enrich across the design, innovation and prototyping landscape. Students may choose to participate in any five (for one credit), ten (for two credits) or fifteen (for three credits) activities. Each week, participating students will attend the scheduled activity, and then create a meaningful response that reflects the impact of that activity on their thinking or practice. Repeatable.

Grading Basis: Letter Grade

Repeatable. Max Credits: 9.

Typically Offered: Fall.

As a student of this Study Abroad program, you will travel to the Trifinio clinic to learn what it takes to provide quality medical care in rural settings and work alongside community members to design new innovative solutions to real world problems. Cross-listed with BIOE 5600

Grading Basis: Letter Grade

Typically Offered: Summer.

In this course, you will learn about: • Structure, function, and biophysical properties of the extracellular matrix (ECM) • How the ECM impacts cell and tissue function • Strategies for engineering ECM-inspired scaffolds Cross-listed with BIOE 5700.

Grading Basis: Letter Grade

Requires prerequisite courses of BIOL 2020 and CHEM 3411 (minimum grade C-).

Typically Offered: Fall.

Covers advanced topics which students may wish to pursue on their own initiative with guidance from department faculty. Credit is awarded upon completion of a project. Department Consent Required. Repeatable.

Grading Basis: Letter Grade

Repeatable. Max Credits: 6.

Department Consent Required. Restriction: Restricted to BIOE-BS majors.

Department of Bioengineering Research Project. Credit may not be applied toward the BS in Bioengineering degree. Department consent required. Repeatable.

Grading Basis: Letter Grade

Repeatable. Max Credits: 6.

Department Consent Required. Restriction: Restricted to BIOE-BS majors.