Overview
The Structural Biology, Biochemistry and Biophysics (STBB) PhD Program is an interdepartmental graduate training program offered within the School of Medicine at the University of Colorado Anschutz Medical Campus in Aurora, Colorado. Student training places a major emphasis on research experiences, both in lab rotations and thesis projects, and includes a range of coursework in biochemistry, biophysics, drug design, pharmacology, and cellular, molecular, and structural biology.
The STBB Program encourages students to engage in collaborative projects and provides shared mentoring that can include faculty from outside The Program. Such interactions are geared towards fostering interdisciplinary training.
Faculty research activities cover a range of structural and computational techniques including NMR Spectroscopy, X-Ray Crystallography, Cryo-EM, Mass Spectrometry and Proteomics, Biophysics, and Peptide/Protein Chemistry that are focused on a diversity of biological targets such as signaling molecules, transmembrane proteins, RNA, genome bioinformatics, lipids, and oligosaccharides.
Admissions Requirements
Admission Philosophy
Student are considered and selected on the basis of past academic performance, previous research experience, recommendations, and individual interviews. While previous experience in structural biology and biochemistry coursework and research is helpful, the STBB program welcomes applicants with varied backgrounds. Students most likely to succeed have traditionally been those with intellectual achievement and creativity, first-hand understanding of laboratory research, and a strong personal desire and motivation to progress in their scientific training.
Entrance Requirements
Students are selected on the basis of past academic performance and, where possible, individual interviews. We select students who show intellectual vigor, independence, and strong motivation to become creative and successful scientists. The faculty recognizes that students who are attracted to a career in Structural Biology and Biochemistry come from highly varied backgrounds. Although there are no specific undergraduate course requirements, students with a good undergraduate foundation in math and the biological and chemical sciences have performed best in the Program. It is suggested that applicants have completed courses in biology, chemistry, biochemistry, and cell and molecular biology before entering the Program.
The Structural Biology and Biochemistry Program requires that applicants achieve a minimum cumulative undergraduate GPA of 3.0, and recommends that applicants complete the Graduate Record Examination (GRE). Foreign applicants must demonstrate proficiency in English.
How to Apply
DEADLINE FOR APPLICATIONS IS DECEMBER 1st.
PRIORITY DEADLINE FOR INTERNATIONAL APPLICANTS IS NOVEMBER 1.
To apply for admission applicants must submit the following:
- Online Graduate School application.
- A $50.00 domestic and $75.00 international non-refundable application fee [credit card (on-line only), check, or money order]. No application will be processed unless this fee is paid.
- Three (3) letters of recommendation. The most informative letters will come from Professors who have mentored you in your research experiences. Professors who have taught science classes you have been enrolled in, or whom you have worked with in an advisory capacity, are also good choices. We do not recommend that you ask postdocs, technicians or fellow students for letters. Likewise, members of the community are generally not good choices, as typically their understanding of biomedical PhD training, and hence their ability to evaluate your potential, is limited.
- GRE test scores are optional but recommended. Use GRE code 4875.
- TOEFL or IELTS scores and financial support verification (international students only).
- One (1) official transcript of all academic work completed to date. To be considered "official", the transcripts must come from the issuing institution directly to the University of Colorado Denver Graduate Admissions.
Electronic Transcripts should be sent to: graduate.school@cuanschutz.edu
If sending a physical transcript, please mail to:
University of Colorado Denver
Graduate School
Mail Stop C296
Fitzsimons Building, W5107
13001 E. 17th Place
Aurora, CO 80045
Degree Requirements
First Year
Code | Title | Hours |
---|---|---|
Fall | ||
BMSC 7806 | Core I: Foundations in Biomedical Sciences | 6 |
BMSC 7810 | Core Topics in Biomedical Science A Discovering Protein Structure & Function | 2 |
BMSC 7810 | Core Topics in Biomedical Science Student Choice | 2 |
STBB 7650 | Research in Structural Biology & Biochemistry 001 | 1-10 |
STBB 7650 | Research in Structural Biology & Biochemistry 002 | 1-10 |
STBB 7660 | Structure Seminar | 1 |
Code | Title | Hours |
---|---|---|
Spring | ||
STBB 7609 | Biophysics & Spectroscopy | 1.5 |
STBB 7610 | Biophysics and Spectroscopy Lab | 1 |
STBB 7650 | Research in Structural Biology & Biochemistry 0V3 | 1-10 |
STBB 7660 | Structure Seminar | 1 |
Electives as Desired |
Code | Title | Hours |
---|---|---|
SUMMER | ||
STBB 8990 | Doctoral Thesis | 1 |
Second Year
Code | Title | Hours |
---|---|---|
Fall | ||
STBB 7650 | Research in Structural Biology & Biochemistry 0V3 | 1-10 |
STBB 7660 | Structure Seminar | 1 |
BMSC 7811 | Responsible Conduct of Research | 1 |
Take 1 course from: | ||
STBB 7631 | Molecular Structure A | 1.5 |
STBB 7632 | Molecular Structure B | 1.5 |
STBB 7633 | Molecular Structure C | 1.5 |
Electives as Desired |
Code | Title | Hours |
---|---|---|
Spring | ||
STBB 7650 | Research in Structural Biology & Biochemistry 0V3 | 1-10 |
Electives as Desired |
Code | Title | Hours |
---|---|---|
SUMMER | ||
STBB 8990 | Doctoral Thesis | 1 |
Third Year & Beyond
Code | Title | Hours |
---|---|---|
Take 30 credits through duration of program: | ||
Enroll in 5 credits (Fall/Spring); 1 credit (Summer) | ||
STBB 8990 | Doctoral Thesis | 1-10 |
Learning Objectives
Goals of the Program
The goals of the Structural Biology, Biochemistry and Biophysics Program are to:
- Foster scientific excellence and innovation in the field of bimolecular structure and function.
- Develop and advance expertise and technology to support cutting-edge research in biomedical sciences
- Provide training and career development for outstanding scientists
- Identify and characterize molecular targets and develop innovative therapeutics and diagnostic tools
- Exploit discoveries and intellectual properties through strategic partnerships with the industry.
Learning Outcomes
The PhD program in Structural Biology, Biochemistry and Biophysics trains graduate students to become proficient and successful investigators who are able to:
- Demonstrate a basic knowledge of central concepts in the biomedical sciences.
- Understand the current concepts in structural biology and biochemistry.
- Read and critically evaluate the scientific literature.
- Formulate hypotheses based on current concepts in the field and design, conduct, and interpret their own research projects.
- Present research results in peer-reviewed publications and in a dissertation.
- Communicate research results effectively through oral presentations at scientific seminars, conferences, and other venues.
- Write a competitive application for research funding.
- Develop ancillary skills, where necessary, to obtain positions outside of scientific research.
With this knowledge, they will understand molecular structures and mechanisms. Training is provided in the following exciting areas:
- Biomolecular Interactions.
- Protein and RNA structure, function, and dynamics.
- Computational studies of structure and function relationships of biomolecules.
- Structure-based design of new molecules important in biology, biochemistry, and pharmacology.
- Proteomics and metabolics.
The courses and research emphasize both breadth and flexibility while encouraging interdisciplinary training. Students may choose research projects from a variety of laboratories at the University of Colorado and the National Jewish Medical and Research Center. Training will result in a PhD degree awarded by the Program in Structural Biology and Biochemistry.
Courses
Contact Us
Catherine Musselman, PhD
Associate Professor
Program Director
catherine.musselman@cuanschutz.edu
Katherine Doyle
Program Administrator
katherine.doyle@cuanschutz.edu
STBB@cuanschutz.edu
University of Colorado Anschutz Medical Campus
12800 E. 19th Avenue
Mailstop 8300
Aurora, CO 80045