2025-2026 Academic Catalog

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Pharmacology and Molecular Medicine (PhD)

Admissions Requirements

To apply for admission applicants must submit the following:

  • Online Graduate School application.
  • A $50.00 domestic and $75.00 international non-refundable application fee [credit card (on-line only), check, or money order]. No application will be processed unless this fee is paid.
  • One (1) official transcript of all academic work completed to date. To be considered "official", the transcripts must come from the issuing institution directly to the University of Colorado Denver Graduate Admissions.

Electronic Transcripts should be sent to: graduate.school@cuanschutz.edu

If sending a physical transcript, please mail to:

University of Colorado Denver
Graduate School
Mail Stop C296
Fitzsimons Building, C5000
13001 E. 17th Place
Aurora, CO 80045

  • Four (4) letters of recommendation.
  • TOEFL or IELTS scores and financial support verification (international students only).

Degree Requirements

First Year

Plan of Study Grid
Year 1
FallHours
BMSC 7806 Core I: Foundations in Biomedical Sciences 6
BMSC 7810 Core Topics in Biomedical Science 2
BMSC 7810 Core Topics in Biomedical Science 2
PHCL 7600 Frontiers in Pharmacology 1
PHCL 7605 Responsible Conduct of Research 1
PHCL 7650 Research in Pharmacology Section 001 1-5
PHCL 7650 Research in Pharmacology Section 002 1-5
 Hours14-22
Spring
PHCL 7606 Receptors and Cell Signaling 3
PHCL 7620 Principles of Pharmacology Section 001 6
PHCL 7650 Research in Pharmacology Section 003 1-5
 Hours10-14
Summer
PHCL 8990 Doctoral Thesis Section 0V1 1-10
 Hours1-10
 Total Hours25-46

Second Year

Plan of Study Grid
Second Year
FallHours
BMSC 7820 Statistics and Data Analyses for the Biomedical Sciences 3
PHCL 7613 Pharmacology Journal Club Section 001 1
PHCL 7615 Grant Proposals in Pharmacology Section 001 1
Elective  
 Hours5
Spring
PHCL 7613 Pharmacology Journal Club Section 001 1
PHCL 7615 Grant Proposals in Pharmacology Section 001 1
PHCL 8990 Doctoral Thesis Section 0V1 1-10
Elective  
 Hours3-12
Summer
PHCL 8990 Doctoral Thesis Section 0V1 1-10
 Hours1-10
 Total Hours9-27

Third Year

Plan of Study Grid
Year 3
FallHours
PHCL 7613 Pharmacology Journal Club Section 001 1
PHCL 8990 Doctoral Thesis Section 0V1 1-10
 Hours2-11
Spring
PHCL 7613 Pharmacology Journal Club Section 001 1
PHCL 8990 Doctoral Thesis Section 0V1 1-10
 Hours2-11
Summer
PHCL 8990 Doctoral Thesis Section 0V1 1-10
 Hours1-10
 Total Hours5-32

Fourth Year & Beyond

Plan of Study Grid
Year 4
FallHours
PHCL 8990 Doctoral Thesis Section 0V1 1-10
 Hours1-10
Spring
PHCL 8990 Doctoral Thesis Section 0V1 1-10
 Hours1-10
Summer
PHCL 8990 Doctoral Thesis Section 0V1 1-10
 Hours1-10
 Total Hours3-30

Learning Objectives

1A. Graduate education in general | Doctoral education is the foundation of future scholarship and the primary “engine” driving the research enterprise.  It prepares future faculty and leaders in the academy as well as in many other areas of industry, government, and society in general.

1B. Pharmacology program in specific | The excellence of our Graduate Program in Pharmacology is best illustrated by the fact that our NIH-sponsored pre-doctoral T32 Training Grant has been continuously funded since 1978, making it one of the longest standing  pharmacology training programs of this type.

The philosophy of our graduate program is to emphasize state-of-the-art research approaches at all stages; and that begins with the recruitment phase. We identify candidates with excellent undergraduate academic credentials, with a strong preference for those who have participated in independent research. During the first year in the program, students must complete three formal laboratory-based research rotations. Each research rotation is intended to examine testable hypotheses, as well as to provide exposure to new laboratory techniques. At the conclusion of each rotation, a post-rotational seminar is presented to the Department. To enhance research exposure further, the Department offers a special course on Frontiers in Pharmacology to our first-year students.

During the first two years in the program, students are required to take a number of courses to prepare them for research careers in pharmacology. These include a core course in molecular and cellular biology overseen by the Graduate School, and Program core courses in Cell and Molecular Signaling and Principles in Pharmacology. Additional requirements include courses in Ethics, Biostatistics, and Reproducibility & Rigor. During  the second year, a number of electives are also available emphasizing topics such as: neuropharmacology/neurobiology and cancer biology, bioinformatics, and structural biology.

The Ph.D. program in pharmacology trains graduate students to become proficient and successful investigators who are able to:

  • Demonstrate a basic knowledge of central concepts of the biomedical sciences.
  • Understand the historical basis as well as current concepts in the scientific discipline of pharmacology.
  • Read and critically evaluate scientific literature relevant to pharmacology, in specific, and the basic and clinical biomedical sciences, in general.
  • Formulate hypotheses based on current concepts in the field and design, conduct, and interpret their own research projects.
  • Writing: Present research results in peer-reviewed publications and in their doctoral dissertation.
  • Speaking: Communicate research results effectively through oral presentations at scientific seminars, conferences, and other venues.
  • Understand the basis of writing and submitting competitive applications for research funding.
  • Develop ancillary skills, where necessary, to obtain positions outside of scientific research.
  • Be competent in self-evaluation of acquired skills and understand how those skills may be perceived by external peers.
  • Develop a mature and meaningful Personal Development Plan (PDP) that will facilitate attainment of career objectives.

Courses

BMSC 7806 -  Core I: Foundations in Biomedical Sciences  (6 Credits)  
Course will focus on the fundamental principles of biomedical sciences. Lectures and recitations/discussions will primarily address the basics of molecular biology, biochemistry, genetics, cell biology and energetic principles. Course is typically limited to biomedical science PhD and BSBT MS students. Previously offered as IDPT 7806
Grading Basis: Letter Grade
Repeatable. Max Credits: 6.
Typically Offered: Fall.
BMSC 7810 -  Core Topics in Biomedical Science  (2 Credits)  
Sections focus on different core topics in biomedical science, and will address subject areas such as protein structure and function, neurobiology, embryology, stem cell research, and cancer biology. Students can enroll in multiple Core Topic Courses topics in one semester. Previously offered as IDPT 7810.
Grading Basis: Letter Grade
Repeatable. Max Credits: 20.
AMC-PHD PhD Students only
Typically Offered: Fall.
BMSC 7811 -  Responsible Conduct of Research  (1 Credit)  
This course provides training in the responsible conduct of biomedical research. It is geared towards early PhD graduate students and meets NIH guidelines. Ethical issues associated with specific topics commonly encountered by graduate students are presented and discussed.
Grading Basis: Letter Grade
Typically Offered: Fall.
BMSC 7820 -  Statistics and Data Analyses for the Biomedical Sciences  (3 Credits)  
This is an introductory course designed for students seeking a basic understanding of statistical concepts and applications. Students will develop statistical literacy and will be taught how to perform basic data analyses, including data summarization, graphical skills, and simple statistical methods for estimation and hypothesis testing. Students will learn how to read and evaluate statistical writing and how to write basic statistical methods. The course will include limited statistical computer programing using the R programming language. The course will not focus on mathematical formulas but will rather focus on building students’ intuition and familiarity with statistical concepts. We will cover concepts such as random sampling, formulating proper hypotheses, bias, power and sample size, and multiple testing. Statistical methods will include both binary and continuous outcomes, including binomial testing, chi-square tests, t-tests, non-parametric tests and basic linear regression. Course examples will prioritize biologic examples routinely encountered in medical research studies. Prerequisites: Prospective students must be enrolled in a ORE graduate program or have explicit permission from the instructor.
Grading Basis: Letter Grade with IP
Typically Offered: Fall.
PHCL 7600 -  Frontiers in Pharmacology  (1 Credit)  
Course is intended to introduce students to cutting-edge pharmacology research and to the range of research opportunities available within the Pharmacology Training Program. Pharmacology Department faculty presentations will focus on cellular signaling, molecular mechanisms of drug actions, structure-based drug design.
Grading Basis: Letter Grade
A-GRAD Restricted to graduate students only.
Typically Offered: Fall.
PHCL 7606 -  Receptors and Cell Signaling  (3 Credits)  
This elective course presents an in-depth treatment of the role of receptors and signal transduction systems in the regulation of cell functions through faculty-presented lectures and student-led discussions of current literature. Prereq: IDPT 7811, 7812, 7813, 7814, 7815.
Grading Basis: Letter Grade
Typically Offered: Spring.
PHCL 7613 -  Pharmacology Journal Club  (1 Credit)  
The overall goal of the course is to teach the students to read and discuss current literature in their field and to gain a comprehensive view of the directions that lead to high-impact research. Students will present and discuss papers.
Grading Basis: Satisfactory/Unsatisfactory w/IP
Repeatable. Max Credits: 1.
Typically Offered: Fall, Spring.
PHCL 7615 -  Grant Proposals in Pharmacology  (1 Credit)  
We will learn principles of good grants(wo)manship and hone our skills in homework assignments and discussions. Our goal is to enable a better learning experience during comps proposal writing, by gaining the tools for optimized self-assessment. Prereq: IDPT 7811, IDPT 7812 ,IDPT 7813, IDPT 7814, IDPT 7815.
Grading Basis: Letter Grade
A-GRAD Restricted to graduate students only.
Typically Offered: Fall.
PHCL 7620 -  Principles of Pharmacology  (6 Credits)  
Lectures are provided in the general areas of pharmacokinetics, receptor theory, structure-activity relationships, drug metabolism, basic pharmacological mechanisms with a particular emphasis on systems such as the nervous system and cardiovascular system, as well as cancer and microbial chemotherapy. Prereq: IDPT 7811, 7812, 7813, 7814, 7815. Restriction: Consent of Course Directors.
Grading Basis: Letter Grade
A-GRAD Restricted to graduate students only.
Typically Offered: Spring.
PHCL 7650 -  Research in Pharmacology  (1-5 Credits)  
Research work in pharmacology. Prereq: Consent of Instructor.
Grading Basis: Letter Grade with IP
Repeatable. Max Credits: 99.
A-GRAD Restricted to graduate students only.
Typically Offered: Fall, Spring, Summer.
PHCL 8990 -  Doctoral Thesis  (1-10 Credits)  
Doctoral thesis work in pharmacology. Prereq: Consent of Instructor.
Grading Basis: Letter Grade with IP
Repeatable. Max Credits: 10.
A-GRAD Restricted to graduate students only.
Additional Information: Report as Full Time.
Typically Offered: Fall, Spring, Summer.

Policies

Please refer to the Graduate School Policies page.

Contact Us

Jim Costello, PhD
Associate Professor
Program Co-Director
james.costello@cuanschutz.edu 

Jason Aoto, PhD
Assistant Professor
​Program Co-Director
jason.aoto@cuanschutz.edu

Vanessa Martinez
Program Administrator
VANESSA.5.MARTINEZ@CUANSCHUTZ.EDU
PHCL@cuanschutz.edu 
303-724-3565