Research work in Integrated Physiology. Prerequisite: Consent of Instructor.

Grading Basis: Letter Grade with IP

Repeatable. Max Credits: 99.

A-GRAD Restricted to graduate students only.

Typically Offered: Fall, Spring, Summer.

Interactive seminar introduces key concepts in clinical study design, basic statistics, & clinical research assessment. Become familiar with clinical study types; rigorously assess the literature; and appreciate how to incorporate clinical data in bench research. Requires presentations, manuscript review, and discussion. Pre-Req: Successful completion of the first year of PhD courses or two years of MSTP training.

Grading Basis: Letter Grade

Typically Offered: Fall.

This course provides instruction in a specialized area of Integrated Physiology. Course content and the extent of the course varies from year to year. Prerequisite: Enrollment in PhD Program in Graduate School.

Grading Basis: Letter Grade

Repeatable. Max Credits: 3.

A-GRAD Restricted to graduate students only.

Typically Offered: Fall, Spring, Summer.

The course will provide an understanding of the function, regulation and integration of human organ systems. Content will include introductory to cell physiology and all major organ systems and will be taught by experts in each organ system.

Grading Basis: Letter Grade

Typically Offered: Spring.

Endocrine systems will be covered from the molecule to the systems level. Pituitary secretions actions/ regulation, regulation of water, ion, calcium balance, regulation of metabolism including insulin secretion/action will be discussed, the context of normal physiology, the mechanisms of endocrine dysfunction. Prereq: Core courses IDPT 7811, 7812, 7813, 7814, 7815. Restrictions: CU-AMC Graduate students; others by permission of the Course Director.

Grading Basis: Letter Grade

A-GRAD Restricted to graduate students only.

Typically Offered: Spring.

This course is a practical workshop in grant-writing culminating in a student-led mock review panel including course participants. Students will examine various proposal types/formats, then write their own proposal in the format of an NIH NRSA fellowship application. Pre-Requisite: Students with adequate physiology background.

Grading Basis: Letter Grade

Typically Offered: Spring.

1. Develop a thorough understanding of the general principles of cell signaling in mammalian physiology. a. Develop a basic understanding of signaling via GPCRs, nuclear receptor signaling and non-classical mechanisms. b. Understand signaling mechanisms in skeletal and cardiac muscle physiology. c. Understand signaling mechanisms in the central nervous system, pulmonary, cardiac, gastrointestinal, renal systems, immunology and bone physiology. d. Understand signaling mechanisms in basic reproductive and fetal physiology. 2. Critically integrate cell signaling in normal physiological context to diseases in some of the physiological systems (not too much focus on cancers per se). 3. This course assesses development and acquisition of core foundational knowledge in signaling mechanisms that orchestrate and integrate physiological systems. 4. The course is divided into 9 units covering signaling in: Muscle and Cardiovascular Physiology, Pulmonary Physiology, Renal Physiology, GI Physiology, Endocrine and Metabolic, Immune system and Hematological, Bone, Reproductive, and Neural.

Grading Basis: Letter Grade with IP

Typically Offered: Spring.

Proteomics is a large-scale analytical approach to examine the functional output of the genome. Many cellular and molecular phenotypes including protein post-translational modifications, protein-protein interactions, and protein localization can only be feasibly discerned at the proteome level. This course provides information on the fundamentals of proteomics for students interested in analyzing large scale protein experiments. The course comprises eight lectures on experimental and analytical considerations, and eight hands-on workshop session. A gentle introduction to R and scientific programming is included, followed up hands-on access, analysis, and visualization of proteomics data using R and popular software tools.

Grading Basis: Letter Grade with IP

Typically Offered: Spring.

Students select topics of interest in the area of cell signaling and receive one-on-one instruction from expert faculty. Each one-credit topic will be taught for 5 weeks. Course work will include reading and discussing papers as well as practical exercises. Prereq: Consent of Instructor

Grading Basis: Letter Grade

Repeatable. Max Credits: 9.

A-GRAD Restricted to graduate students only.

Typically Offered: Fall, Spring, Summer.

Doctoral thesis work in physiology.

Grading Basis: Letter Grade with IP

Repeatable. Max Credits: 99.

A-GRAD Restricted to graduate students only.

Additional Information: Report as Full Time.

Typically Offered: Fall, Spring, Summer.